Cross-species ion channel classification with multimodal graph neural networks; persistent homology mitigates phylogenetic leakage in protein classifiers
Read the original at arxiv.org→arXiv:2610.30394v1 Announce Type: new Abstract: Protein classifiers are highly sensitive to evaluation protocol: random train/test splits induce phylogenetic leakage, allowing models to exploit taxon-specific...
Original headline: "Escaping the Phylogenetic Trap: Persistent Homology Enables Cross-Species Ion Channel Classification via Multimodal Graph Neural Networks"
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- Oct 23, 04:00 UTC arXiv cs.LG lead source Escaping the Phylogenetic Trap: Persistent Homology Enables Cross-Species Ion Channel Classification via Multimodal Graph Neural Networks